S. Mouffak, S. Berrada, Pr. M. Hassani, J. Kouach And D. Moussaoui.
Adult Still\'s disease (ASD) is a auto inflammatory disease so-called polygenic. ASD is a rare pathology known as benign, its diagnosis remains a diagnosis of elimination based on the set of polymorphic clinical signs (fever, rash and or arthralgia), with 2 forms, systemic and articular. Thus, in the absence of a specific diagnostic marker, the ASD remains a diagnosis of elimination.
The interaction between ASD and pregnancy is poorly known, the literature is still poor given its rarity, the number of published observations does not exceed thirty, so its discovery during pregnancy can may compromise the outcome of pregnancy, rarely a life-threatening of the mother.disease flares can occur during ASD in the 2nd trimester and in the postpartum. Corticosteroid therapy is the first-line treatment of ASD, probably more effective in systemic forms of the disease.
We recall here this pathology through the case of a patient who during 10 years of evolution of MSA, in its corticodependent systemic form, had carried out 3 pregnancies without resonance or dysgravidia.
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Dr Saloni Sethi, Dr Aditi Arora, Dr Vikash Kumari Kasana, Dr Premlata Mital , Dr Ishita Agarwal, Dr Isha Ramneek and Dr Sakshi Bansal
During pregnancy calcium demand increases due to increase requirement by the developing foetus. This demand is met by dietary calcium intake. Physiological changes in pregnancy tend to lower calcium and calcium homeostasis is maintained by various hormones. The present study was done to find association of sociodemographic factors of the pregnant women with hypocalcaemia.
Material and methods: 100 women in their third trimester of pregnancy were included in the study after obtaining written informed consent. After detail history and examination, 5 ml venous blood is collected to measure serum ionic calcium. Data were entered in to MS Excel sheet and analysed.
Results: Normal serum ionic calcium range is 4.2 – 5.5 mg%. Out of 100 women 36% women had hypocalcaemia. There was no significant association between hypocalcaemia and age (p=0.8), residence (p=0.6), religion (p=0.1), socio-economic status (p=0.8). There was significant association between hypocalcaemia and literacy status (p-0.02). Women with past history of preterm birth and abortion had more risk of having hypocalcaemia. There was a negative correlation between maternal age and mean serum ionic calcium level.
Conclusion: Hypocalcaemia is common in pregnancy. Hypocalcaemia was more common in women who were above 25 years of age, muslim, illiterate, belonging to lower and middle socio-economic status and multiparous. Risk of hypocalcaemia was more in women with gestational age below 34 weeks. All women in their antenatal period should be screened for hypocalcaemia and calcium should be supplemented routinely to all women during antenatal period.
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