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The toxicity of heavy metals when their concentration exceeds allowable limits has made their presence in our environment of great concern. These metals are released into the environment through a range of sources, including industrial processes into nearby rivers thereby polluting the river for domesticated usage. Thirty-six male, healthy rats (Rattus novergicus) were purchased from the Animal House and given water samples from the Asa River in different concentrations (20, 40, 60, 80, and 100%). Rats from the experimental and control groups were sacrificed and the liver and kidney were removed, washed in 10% formal saline, and prepared for histomorphological examinations. Rats\' blood was also taken for haematological and biochemical indices during the animal sacrifice processess. In this study, Alanine amino transferase (ALT )and Aspartate amino transferase (AST) levels at higher concentrations were significantly noted when compared to the control group resulting to alteration of the liver and kidney organs at higher concentrations with mild periportal cellular infiltration and mild congestion of the renal interstitium and severe congestion and hemorrhage at the renal interstitium, respectively. Rats\' haematological and biochemical indices did not differ significantly from the control group.

This study evaluated the haematological and serum biochemical indices of broiler chickens fed diets containing varying inclusion levels of sun-dried false yam meal (SFYM) as a partial replacement for maize. A total of 150-day-old broiler chicks were randomly assigned to five dietary treatments (0, 4, 8, 12 and 16% SFYM inclusion) in a completely randomized design (CRD), with three replicates of ten birds per treatment. Data on haematological indices showed that increasing SFYM levels led to a significant (P<0.05) decrease in packed cell volume (PCV), red blood cell (RBC), MCV, MCH, MCHC, and percentage heterophil, whilst the WBC increases. The mean corpuscular volume (MCV) and mean corpuscular haemoglobin (MCH) declined with increasing SFYM levels, indicative of a microcytic, hypochromic effect. Percentage eosinophil and lymphocytes were significantly (P<0.05) higher in broiler chickens maintained in T2 and T5 respectively compared to other treatment groups. The serum biochemical indices revealed (P<0.05) reduction in total protein, glucose, ALP, and AST of broiler chickens as the inclusion levels of SFYM increased, while the concentration of albumin, urea and creatinine increased. These findings suggest that SFYM can be used to substitute maize partially up to 16% level without negative impact on broiler chickens health.